Author

C. L. Drum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

L. S. Pakkiri· 2 shared A. A. Widjaja· 1 shared A. F. Vallejo· 1 shared A. Hearn· 1 shared B. K. Singh· 1 shared B. NG· 1 shared B. Vilaysane· 1 shared C. Bai· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPathology

L. S. Pakkiri

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2 papers

Recent·Most cited

MMPs and NETs are detrimental in human CNS-tuberculosis and MMP inhibition in a mouse model improves survival

X. Y. Poh, F. K. Loh, C. Bai, H. T. Chong, W. K. Teo, J. M. Hong, Q. H. Miow, P. M. Thong, B. Vilaysane, T. H. Hu, S. Chhabra, Y. Wang, S. C. Tiong, S. M. Fong, M. Kamihigashi, , C. W. M. Ong

The paper identifies elevated MMPs and NETs in CNS-TB patients and shows MMP inhibition improves survival in a mouse model.

bioRxiv · Oct 5, 2023 · PreprintPathology

Redefining Interleukin 11 as a regeneration-limiting hepatotoxin

A. A. Widjaja, J. R. Dong, E. Adami, S. Viswanathan, B. NG, B. K. Singh, W.-W. Lim, J. Zhou, L. S. Pakkiri, S. G. Shekeran, J. Tan, S. Y. Lim, M. Wang, R. Holgate, A. Hearn, , S. A. Cook

This study reveals IL11 as a hepatotoxin that limits liver regeneration after APAP overdose, showing its inhibition of endogenous IL11 activity protects mice.

bioRxiv · Nov 4, 2019Physiology