Author

C. Bai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Pathology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Organism:mouse· 5 Research Focus:cell type annotation· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Research Focus:differential expression· 2

Frequent Co-Authors

Y. Wang· 3 shared C. S. L. Ding· 2 shared C. W. M. Ong· 2 shared G. Gao· 2 shared G. Li· 2 shared J. M. Hong· 2 shared L. Yang· 2 shared L. Zhou· 2 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersPathology

Y. Wang

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Pro-renin Receptor Inhibited ABCA1/G1 Expression Associated with Low HDL-c and Promoted Atherosclerosis

Y. Dong, W. Zhang, W. Liu, C. Bai, Y. Zhang, Y. Jiang, W. Song

This study shows that prorenin binding to (P)RR inhibits ABCA1/ABCG1 expression and cholesterol efflux, leading to dyslipidemia and atherosclerosis in hypertension.

bioRxiv · Apr 3, 2024 · PreprintPathology

Heterogeneous hybrid immunity against Omicron variant JN.1 at 11 months following breakthrough infection

X. He, J. Jiang, G. Li, J. Liu, J. Gan, L. Zhou, C. Bai, Q. Zi, X. Mou, S. Zeng, J. Yuan, C. Zhou, Y. Li, G. Zhu, R. Zhao, , W. Li

This study evaluates hybrid immunity against the Omicron variant JN.1 11 months after breakthrough infection, showing heterogeneous responses and increased neutralization following reinfection.

bioRxiv · Mar 2, 2024Immunology

MMPs and NETs are detrimental in human CNS-tuberculosis and MMP inhibition in a mouse model improves survival

X. Y. Poh, F. K. Loh, C. Bai, H. T. Chong, W. K. Teo, J. M. Hong, Q. H. Miow, P. M. Thong, B. Vilaysane, T. H. Hu, S. Chhabra, Y. Wang, S. C. Tiong, S. M. Fong, M. Kamihigashi, , C. W. M. Ong

The paper identifies elevated MMPs and NETs in CNS-TB patients and shows MMP inhibition improves survival in a mouse model.

bioRxiv · Oct 5, 2023 · PreprintPathology

Nos2-/- mice infected with M. tuberculosis develop neurobehavioral changes and immunopathology mimicking human central nervous system tuberculosis

X. Y. Poh, J. M. Hong, C. Bai, Q. H. Miow, P. M. Thong, Y. Wang, R. Rajarethinam, C. S. L. Ding, C. W. M. Ong

This study develops a murine model of CNS-TB using Nos2-/- mice infected with M. tuberculosis, showing neurobehavioral changes and immunopathology similar to human CNS-TB.

bioRxiv · Aug 15, 2021Microbiology

Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients

H. Xiang, Y. Zhao, X. Li, P. Liu, L. Wang, M. Wang, L. Tian, H. Sun, W. Zhang, Z. Xu, B. Ye, X. Yuan, P. Wang, N. Zhang, Y. Gong, , P. Yang

This study characterizes the dynamic changes in B-cell receptor repertoires of COVID-19 patients using next-generation sequencing, revealing clonotype overlap, lineage expansion, and V gene usage patterns.

bioRxiv · Dec 28, 2020Immunology

Fibroblast Protection of Borrelia burgdorferi from Doxycycline, Cefuroxime and Daptomycin Combination is Eliminated by Oregano or Carvacrol Essential Oil

C. Bai, H. Yang, P. Cui, R. Quan, Y. Zhang

The paper shows fibroblasts protect B. burgdorferi from a drug combination, but oregano or carvacrol essential oil enhances drug efficacy against the bacteria in fibroblasts.

bioRxiv · Dec 2, 2019 · PreprintMicrobiology

Significant improvement of reprogramming efficiency by transient overexpression of ZGA inducer Dux but not Dppa2/4

L. Yang, X. Liu, L. Song, A. Di, G. Su, C. Bai, Z. Wei, G. Li

This study shows that transient Dux overexpression improves SCNT and chemical reprogramming efficiency, while Dppa2/4 do not, and Dux treatment makes SCNT embryos resemble fertilized embryos.

bioRxiv · Oct 21, 2019 · PreprintBioengineering

Geographic Patterns of Bacterioplankton among Lakes of the Middle and Lower Reaches of the Yangtze River Basin, China

C. Bai, J. Cai, L. Zhou, X. Jiang, Y. Hu, J. Dai, K. Shao, X. Tang, X. Yang, G. Gao

The paper examines geographic patterns of bacterioplankton in interconnected lakes of the Yangtze River Basin, finding that distance-decay relationships and stochastic processes dominate bacterial community assembly.

bioRxiv · Jan 31, 2019Microbiology

Coordinative Metabolism of Glutamine Carbon and Nitrogen in proliferating Cancer Cells Under Hypoxia

Y. Wang, C. Bai, Y. Ruan, M. Liu, Q. Chu, L. Qiu, C. Yang, B. Li

The paper identifies a hypoxia-specific metabolic pathway in cancer cells that redirects glutamine nitrogen to secretory dihydroorotate, avoiding ammonia toxicity and supporting tumor growth.

bioRxiv · Jul 20, 2018Biochemistry