Author

L. Y. Cheng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant calling· 2 Research Focus:variant effect prediction· 2 Assay:DNA methylation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

D. Y. Zhang· 2 shared A. A. Patel· 1 shared A. Pinto· 1 shared K. Zhang· 1 shared L. Rodriguez· 1 shared P. Dai· 1 shared P. Song· 1 shared S. X. Chen· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

D. Y. Zhang

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintAug 12, 2021

Single Tube qPCR detection and quantitation of hotspot mutations down to 0.01% VAF

K. Zhang, L. Rodriguez, L. Y. Cheng, D. Y. Zhang

This paper introduces As-BDA, a method that detects and quantifies rare mutations down to 0.01% VAF using qPCR, with high concordance compared to ddPCR.

DOI 10.1101/2021.08.12.456178

humanDNA methylation

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BioengineeringbioRxivPreprintApr 26, 2020

Detecting and Quantitating Low Fraction DNA Variants with Low-Depth Sequencing

P. Song, S. X. Chen, Y. H. Yan…·D. Y. Zhang

This paper introduces mBDA, a method to detect low-frequency DNA variants with low-depth sequencing, and applies it to find tumor heterogeneity in melanoma samples.

DOI 10.1101/2020.04.26.061747

humanwhole-genome sequencing

𝕏 PostBluesky