Author

Leela Shrestha

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Organism:human· 1

Frequent Co-Authors

Ashley C. W. PikeiD· 2 shared Nicola A. Burgess-BrowniD· 2 shared Andrew QuigleyiD· 1 shared Aytuğ K. KiperiD· 1 shared David B. SaueriD· 1 shared David Speedman· 1 shared Eleanor WilliamsiD· 1 shared Elisabeth P. CarpenteriD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Ashley C. W. PikeORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintNov 3, 2026

Structural Basis for Inhibition of Human Anion Transporter SLC26A6/PAT-1

Gamma Chi, Tina Bohstedt, Roslin Adamson…·David B. Sauer

This study reports cryo-EM structures of human PAT-1 with inhibitors to elucidate their inhibition mechanisms and domain interactions.

DOI 10.64898/2026.11.01.757131

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJul 19, 2019

A unique lower X-gate in TASK channels traps inhibitors within the vestibule

Karin E. J. Rödström, Aytuğ K. Kiper, Wei Zhang…·Elisabeth P. Carpenter

This paper reveals the structure of TASK-1 channels, identifying a unique lower X-gate that traps inhibitors in the vestibule, explaining their slow washout and pharmacological properties.

6 citations

experimental assayprotein structure prediction

𝕏 PostBluesky