Selective induction by statins of FAM134B-mediated sarcoplasmic reticulum (SR)-phagy degrades the SR calcium pump SERCA1 and contributes to myopathy
Liyang Ni, Xiaolin Zhao, Lirong Zheng…·Yoshio Yamauchi
This study identifies FAM134B-mediated SR-phagy as a mechanism by which statins induce myopathy by degrading SERCA1.