Cancer BiologybioRxiv
Multiplexed single-cell lineage tracing of mitotic kinesin inhibitor resistance in glioblastoma
Y. L. Cheng, M. A. Banu, W. Zhao…·P. A. Sims
This study uses lineage tracing and scRNA-seq to analyze drug resistance in glioblastoma cells treated with KIF11 inhibitor ispinesib, finding resistance-associated phenotypic changes and potential drug combinations.