SALLB not targeted by IMiDs is important for maintenance of liver cancer cells
K. A. L. Vu, S. Moein, K. Kumari…·L. Chai
The paper identifies a compound that degrades both SALL4 isoforms, overcoming IMiD limitations in liver cancer treatment.
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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
K. A. L. Vu, S. Moein, K. Kumari…·L. Chai
The paper identifies a compound that degrades both SALL4 isoforms, overcoming IMiD limitations in liver cancer treatment.
B. Q. Trinh, S. Ummarino, A. K. Ebralidze…·D. G. Tenen
The paper identifies the long noncoding RNA LOUP as a mediator of RUNX1 and RUNX1-ETO effects in t(8;21) AML, showing it promotes myeloid differentiation and inhibits cell growth by regulating PU.1 expression.
J. Kwon, Y. V. Liu, C. Gao…·D. G. Tenen
This study identifies a mechanism by which pseudogene 5 induces DNA demethylation and reactivates the oncogene SALL4 in hepatocellular carcinoma, linking HBV infection to HCC progression.