BiophysicsbioRxivPreprint
Entry Pathway for the Inverse Agonist Ligand in the G Protein-Coupled Receptor Rhodopsin
H. Tian, K. M. Gunnison, M. A. Kazmi…·T. Huber
This study investigates the pathway for 11-cis-retinal entry into rhodopsin, finding that it enters through a transmembrane channel between TM5/6, controlled by dynamic allosteric mechanisms.
DOI 10.1101/2021.05.24.445474