M. Akkoyunlu

This study shows IL-6 suppresses TFH cell responses in neonatal mice by enhancing IL-2 activity, while IL-6 deficiency improves vaccine responses.

This study shows neonatal CD19+CD43- B cells produce IL-10 via STAT5-mediated IL-6 secretion upon BCR activation, revealing a novel mechanism for IL-10 production in neonates.

This study shows that soluble CD138 enhances APRIL-mediated B cell survival and autoreactive antibody production in MRL/Lpr mice, contributing to SLE pathology.

This study identifies CD138-expressing T cells in SLE-prone mice, showing their pathogenic role in disease progression and potential as a therapeutic target.