Selenium reduction of ubiquinone via SQOR suppresses ferroptosis
N. Lee, S. J. Park, M. Lange, T. Tseyang, M. B. Doshi, T. Kim, Y. Song, D. Kim, P. L. Greer, J. A. Olzmann, J. Spinelli, D. Kim
The paper shows selenium reduces ubiquinone to ubiquinol via SQOR, protecting against ferroptosis independently of selenoprotein production.
bioRxiv · Apr 13, 2023Biochemistry