S. J. Park

This study shows that IPMK regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling, impacting immune responses and autoimmune disease models.

This study identifies CD20 as an odorant receptor in mice that mediates innate predator avoidance behavior by detecting predator-derived compounds.

The paper shows selenium reduces ubiquinone to ubiquinol via SQOR, protecting against ferroptosis independently of selenoprotein production.

This paper presents a chromosome-level genome assembly of Euphorbia peplus, identifies a gene cluster for ingenol mebutate biosynthesis, and explains its small genome size through restricted Ty3 transposon expansion.

The paper identifies novel resistance genes in Solanum americanum against Phytophthora infestans by analyzing genome variation and effector recognition.

This study identifies lomitapide, a cholesterol-lowering drug, as an mTORC1 inhibitor that induces autophagic cell death in cancer cells and enhances immune checkpoint blockade in preclinical models.

This study identifies three glycolysis enzymes (TPI, GAPC, PGK) that negatively regulate autophagy by monitoring nutrient availability through their interaction with ATG101.

The paper identifies new alleles of the tomato SELF PRUNING gene that alter plant compactness and yield, with sp-5732 increasing yield by up to 42%.

This study shows that IPMK in intestinal epithelial cells protects against colitis by regulating tuft cell development and cholinergic signaling.

This study uses computational metabolomics to analyze resin glycoside diversity in morning glory species, revealing lineage-specific structural variations and biosynthetic pathway diversification.

This study uses AcePET to visualize tumor boundaries and reactive astrocytes in GBM, showing that targeting MCT1 improves survival by enabling complete resection of cancer stem cells.

This study shows that blocking N- and O-glycan biosynthesis reduces SARS-CoV-2 viral entry by affecting Spike protein proteolysis and RBD presentation.

This paper develops novel Kras-mutant murine NSCLC models with increased TMB and co-occurring mutations, showing enhanced anti-PD-1 efficacy but immunosuppressed TMEs in some models.

This study investigates sex differences in ocular HSV-1 infection and Herpes Stromal Keratitis pathogenesis in wild type and HVEM knockout mice, finding no significant sex-based differences in disease outcomes.