FLCN Gene Ablation Reduces Fibrosis and Inflammation in a Diet-Induced NASH Model
M. Paquette, M. Yan, L. El-Houjeiri, M. Biondini, J. M. J. Ramirez-Reyes, A. Pacis, H. Jeong, J. L. Estall, P. M. Siegel, A. Pause
This study shows that FLCN gene ablation reduces fibrosis and inflammation in a diet-induced NASH model by enhancing autophagy and lysosomal biogenesis.
bioRxiv · Sep 10, 2020 · PreprintPathology