Author

M. Bowman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

R. L. Bowman· 2 shared A. Bakayoko· 1 shared A. Battu· 1 shared A. D. Goldberg· 1 shared A. D. Viny· 1 shared A. D'Alessandro· 1 shared A. E. Heath· 1 shared A. Garcia-Sastre· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersCancer Biology

R. L. Bowman

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Chemoresistance of TP53 mutant AML requires the mevalonate byproduct, GGPP, for regulation of ROS and induction of a mitochondria stress response

S. J. Skuli, A. Bakayoko, M. Kruidenier, B. Manning, P. Pammer, A. Salimov, O. Riley, G. Brake-Silla, M. Bowman, L. N. Martinez-Gutierrez, R. Buono, M. Paul, E. Saland, S. Wong, J. Xu, , M. Carroll

This study identifies GGPP, a mevalonate pathway byproduct, as critical for chemoresistance in TP53mut AML through ROS regulation and mitochondria stress response, suggesting statin-based therapies could be effective.

bioRxiv · Jun 7, 2024 · PreprintCancer Biology

ZFAND6 is a subunit of a TRAF2-cIAP E3 ubiquitin ligase complex essential for mitophagy

K. Shaikh, M. Bowman, S. M. McCormick, L. Gao, J. Zhang, J. Tawil, A. Kapoor, R. Arav-Boger, Y. B. Choi, A. Pekosz, S. L. Klein, M. Lanza, J. C. Fanburg-Smith, A. Garcia-Sastre, C. C. Norbury, , E. W. Harhaj

This study identifies ZFAND6 as a component of a TRAF2-cIAP E3 ubiquitin ligase complex that regulates mitophagy, maintaining mitochondrial homeostasis and influencing immune responses to viral infection.

bioRxiv · Mar 27, 2024 · PreprintImmunology

One thousand soils for molecular understanding of belowground carbon cycling

M. Bowman, A. E. Heath, T. Varga, A. Battu, R. K. Chu, J. G. Toyoda, T. Cheeke, S. Porter, K. Moffett, B. Letendre, O. Qafoku, J. Bargar, D. Mans, N. Hess, E. B. Graham

This paper introduces the 1000 Soils Pilot to study belowground carbon cycling using molecular and microstructural analyses, finding that frequent wildfires reduce soil respiration and alter SOM oxidation states and soil structure.

bioRxiv · Dec 12, 2022Ecology

Single cell mutational profiling delineates clonal trajectories in myeloid malignancies

L. A. Miles, R. L. Bowman, T. R. Merlinsky, I. S. Csete, A. Ooi, R. Durruthy-Durruthy, M. Bowman, C. Famulare, M. A. Patel, P. Mendez, C. Ainali, M. Manivannan, S. Sahu, A. D. Goldberg, K. Bolton, , R. L. Levine

This study uses single-cell mutational profiling to analyze clonal trajectories in myeloid malignancies, revealing patterns of mutation acquisition and clonal complexity.

bioRxiv · Feb 7, 2020 · PreprintCancer Biology

Differential Effector Response of Amnion- and Adipose-Derived Mesenchymal Stem Cells to Inflammation; Implications for Intradiscal Therapy

R. Borem, A. Madeline, M. Bowman, S. Gill, J. Tokish, J. Mercuri

This study compares the inflammatory response of amnion- and adipose-derived mesenchymal stem cells in intervertebral disc degeneration, finding AM-MSCs produce more anti-inflammatory cytokines and chondrogenic matrix while AD-MSCs proliferate more and produce pro-inflammatory cytokines.

bioRxiv · Jan 17, 2019Bioengineering