Cancer BiologybioRxiv
Caspase-2 protects against ferroptotic cell death
S. Dawar, M. C. Benitez, Y. Lim…·N. J. Clemons
This study shows caspase-2 protects mutant-p53 cancer cells from ferroptotic death by non-proteolytically interacting with proteins to limit GPX4 degradation.
DOI 10.1038/s41419-024-06560-6