Author

M. C. Coyle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biochemistry· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:development & morphogenesis· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

Z. J. Gartner· 2 shared A. Dar· 1 shared A. J. Hughes· 1 shared A. P. Scopton· 1 shared B. T. Larson· 1 shared C. Combredet· 1 shared C. N. Elya· 1 shared C. Stashko· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBioengineering

Z. J. Gartner

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Environmentally regulated clonal-aggregative multicellularity in a choanoflagellate

N. Ros-Rocher, J. Reyes-Rivera, U. Horo, Y. Foroughijabbari, C. Combredet, B. T. Larson, M. C. Coyle, E. A. T. Houtepen, M. J. A. Vermeij, J. L. Steenwyk, T. Brunet

This study shows that the choanoflagellate Choanoeca flexa forms multicellular sheets through clonal or aggregative mechanisms, adapting to environmental changes in splash pools.

bioRxiv · Mar 25, 2024 · PreprintEvolutionary Biology

A stress-responsive p38 signaling axis in choanoflagellates

F. U. Rutaganira, M. C. Coyle, M. H. T. Nguyen, I. Hernandez, A. P. Scopton, A. Dar, N. King

This study identifies a stress-responsive p38 signaling axis in choanoflagellates using kinase inhibitors, revealing conserved functions across animals, fungi, and choanoflagellates.

bioRxiv · Aug 26, 2022Biochemistry

Microenvironmental engineering improves the self-organization of patterned microvascular networks

K. A. Cabral, V. Srivastava, M. C. Coyle, C. Stashko, V. Weaver, Z. J. Gartner

This study shows that engineering the microenvironment with fibrillar matrices and removing a serum component improves the self-organization of patterned endothelial cells into perfusable microvascular networks.

bioRxiv · Apr 4, 2022 · PreprintBioengineering

Entomophthovirus: An insect-derived iflavirus that infects a behavior manipulating fungal pathogen of dipterans

M. C. Coyle, C. N. Elya, M. J. Bronski, M. B. Eisen

The paper identifies Entomophthovirus, a new iflavirus associated with the fungal pathogen Entomophthora muscae, and shows its presence in multiple dipteran species.

bioRxiv · Jul 18, 2018Microbiology

Tissue Folding by Mechanical Compaction of the Mesenchyme

A. J. Hughes, H. Miyazaki, M. C. Coyle, J. Zhang, M. T. Laurie, D. Chu, Z. Vavrusova, R. A. Schneider, O. D. Klein, Z. J. Gartner

This study shows mechanical compaction of mesenchyme drives tissue folding in vitro through ECM strain and collagen alignment, without genetic engineering.

bioRxiv · Jul 15, 2017Bioengineering