Author

M. Collino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:rat· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

C. Thiemermann· 3 shared E. Aimaretti· 2 shared G. Ferreira Alves· 2 shared N. M. Patel· 2 shared S. M. Coldewey· 2 shared A. Van Dam· 1 shared D. Collotta· 1 shared D. Greaves· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersPharmacology & Toxicology

C. Thiemermann

Mutual co-authors in cluster

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3 papers

Recent·Most cited

OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity

G. Purvis, M. Collino, A. Van Dam, G. Einaudi, Y. Ng, M. Shanmuganathan, S. Patel, C. Thiemermann, K. Channon, D. Greaves

This paper shows that inhibiting BTK in adipose tissue macrophages enhances OxPhos and shifts macrophages to an M2-like state, reducing inflammation and improving metabolic outcomes in obesity.

bioRxiv · Oct 9, 2023Pathology

Inhibition of the JAK/STAT pathway with baricitinib reduces the multiple organ dysfunction caused by hemorrhagic shock in rats

N. M. Patel, D. Collotta, E. Aimaretti, G. Ferreira Alves, S. Kröller, S. M. Coldewey, M. Collino, C. Thiemermann

This study shows that baricitinib reduces multiple organ dysfunction in hemorrhagic shock rats by inhibiting JAK/STAT, NF-κB, and NLRP3 pathways.

bioRxiv · Jan 13, 2022Pharmacology & Toxicology

Inhibition of Bruton's tyrosine kinase activity attenuates trauma-induced multiple organ dysfunction in rats

N. M. Patel, F. R. Oliveira, H. Pillmann Ramos, E. Aimaretti, G. Ferreira Alves, S. M. Coldewey, M. Collino, R. Sordi, C. Thiemermann

This study shows that BTK inhibitors reduce trauma-induced multiple organ dysfunction in rats by inhibiting BTK, NF-κB, and NLRP3 activation.

bioRxiv · Sep 23, 2021Pharmacology & Toxicology