Author

M. D. Hoffmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. C. Zdechlik· 1 shared A. G. Amaral· 1 shared A. Lotfinia· 1 shared B. Morgan· 1 shared C. Bickelmann· 1 shared C. Carlein· 1 shared C. Maack· 1 shared D. Nedrud· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. C. Zdechlik

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pancreatic islets undergo functional and morphological adaptation during development of Barth Syndrome

C. Carlein, M. D. Hoffmann, A. G. Amaral, C. Bickelmann, A. Lotfinia, L.-A. de Selliers, J. Audouze-Chaud, S. Wrublewsky, M. A. Lauterbach, K. von der Malsburg, M. van der Laan, M. Bozem, M. Hoth, P. Gilon, M. Ravier, , L. Prates Roma

The paper investigates how defective cardiolipin remodeling in Barth Syndrome affects pancreatic islet function and metabolism, finding improved glucose tolerance and compensatory metabolic adaptations in a mouse model.

bioRxiv · Jun 28, 2024 · PreprintPhysiology

Multiparametric domain insertional profiling of Adeno-Associated Virus VP1

M. D. Hoffmann, A. C. Zdechlik, Y. He, D. Nedrud, G. Aslanidi, W. Gordon, D. Schmidt

The paper inserts large protein domains into AAV capsid protein VP1 to identify engineerable hotspots and assess capsid robustness to structural modifications.

bioRxiv · Apr 19, 2023Biochemistry