Development of a human glioblastoma model using humanized DRAG mice for immunotherapy
R. Srivastava, A. Labani-Motlagh, A. Chen, F. Yang, D. Ansari, S. Patel, H. Ji, S. Trasti, M. Dodda, Y. Patel, H. Zou, B. Hu, G. Yi
This study develops a humanized DRAG mouse model to test GBM immunotherapy, showing anti-PD-1 antibodies reduce immunosuppressive cells in xenografted tumors.
bioRxiv · Feb 15, 2023Cancer Biology