Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors
S. S. Neuman, J. M. Metzger, V. Bondarenko, Y. Wang, J. Felton, J. E. Levine, K. Saha, S. Gong, M. E. Emborg
The paper shows that genome editing in the striatum leads to fluorescent reporter expression in the substantia nigra pars reticulata via anterograde axonal transport.
bioRxiv · Jun 21, 2023Bioengineering