Author

M. E. Garrett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Approach:deep learning· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:behavioral assay· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

H. Y. Chu· 4 shared J. Overbaugh· 4 shared F. A. Matsen· 3 shared J. K. Logue· 3 shared C. I. Stoddard· 2 shared H. L. Itell· 2 shared J. G. Galloway· 2 shared K. Sung· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersImmunology

H. Y. Chu

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Author profile →

6 papers

Recent·Most cited

The S2 subunit of spike encodes diverse targets for functional antibody responses to SARS-CoV-2

J. Guenthoer, M. E. Garrett, M. Lilly, D. M. Depierreux, F. Ruiz, M. Chi, C. I. Stoddard, V. Chohan, K. Sung, D. Ralph, H. Y. Chu, F. A. Matsen, J. Overbaugh

This paper identifies diverse functional antibodies targeting the S2 subunit of SARS-CoV-2 spike, including one with broad neutralization activity across multiple coronaviruses.

bioRxiv · Feb 26, 2024 · PreprintImmunology

Macaque-human differences in SARS-CoV-2 Spike antibody response elicited by vaccination or infection

A. Willcox, K. Sung, M. E. Garrett, J. G. Galloway, M. A. OConnor, J. H. Erasmus, J. K. Logue, D. W. Hawman, H. Y. Chu, K. J. Hasenkrug, D. H. Fuller, F. A. Matsen, J. Overbaugh

This study compares SARS-CoV-2 Spike antibody responses between macaques and humans after vaccination or infection, identifying shared and distinct epitope recognition patterns and escape pathways.

bioRxiv · Dec 1, 2021 · PreprintImmunology

Comprehensive characterization of the antibody responses to SARS-CoV-2 Spike protein after infection and/or vaccination

M. E. Garrett, J. G. Galloway, C. Wolf, J. K. Logue, N. Franko, H. Y. Chu, F. Matsen, J. M. Overbaugh

This study characterizes antibody responses to SARS-CoV-2 Spike protein after infection and vaccination, identifying epitope binding patterns and escape mutation profiles.

bioRxiv · Oct 5, 2021Immunology

High resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies

M. E. Garrett, J. Galloway, H. Y. Chu, H. L. Itell, C. I. Stoddard, C. R. Wolf, J. K. Logue, D. McDonald, F. A. Matsen, J. Overbaugh

This study identifies antibody escape pathways for SARS-CoV-2 spike protein using Phage-DMS, revealing variable escape mutations in immunodominant regions and individual epitope targeting differences.

bioRxiv · Nov 16, 2020Immunology

Phage-DMS: a comprehensive method for fine mapping of antibody epitopes

M. E. Garrett, H. L. Itell, K. H. D. Crawford, R. Basom, J. D. Bloom, J. Overbaugh

Phage-DMS combines immunoprecipitation of phage peptide libraries with deep mutational scanning to fine map antibody epitopes, refining known epitopes for HIV monoclonal antibodies.

bioRxiv · May 11, 2020Immunology

Quantifying and Modelling Transfer Learning in Mice Between Consecutive Training Stages of a Change Detection Task

I. Magrans de Abril, M. E. Garrett, D. R. Ollerenshaw, P. A. Groblewski, S. Olsen, S. Mihalas

This paper studies transfer learning in mice during a change detection task, finding that performance drops when transitioning to more complex stages and proposing a cognitive model based on deep Q learning with representation remapping.

bioRxiv · Dec 19, 2019 · PreprintAnimal Behavior & Cognition