Author

M. Eddy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Duong· 1 shared A. Ray· 1 shared A. Wijesekara· 1 shared B. Jin· 1 shared C. McCurdy· 1 shared E. Lyman· 1 shared E. Petracco· 1 shared G. Ferre· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Duong

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2 papers

Recent·Most cited

Visualizing the impact of disease-associated mutations on G protein-nucleotide interactions

K. Anazia, L. Koenekoop, G. Ferre, E. Petracco, H. Gutierrez-de-Teran, M. Eddy

This study investigates how disease-associated mutations in G protein subunits affect nucleotide interactions using spectroscopic and computational methods, revealing distinct structural and functional changes.

bioRxiv · Jan 30, 2024Biophysics

Anionic Phospholipids Control Mechanisms of GPCR-G Protein Recognition

N. Thakur, A. Ray, L. Sharp, B. Jin, A. Duong, N. Gopal Pour, S. Obeng, A. Wijesekara, Z.-G. Gao, C. McCurdy, K. A. Jacobson, E. Lyman, M. Eddy

This study shows anionic lipids facilitate GPCR-G protein complex formation through conformational selection, with computational models supporting charge complementarity as a general mechanism.

bioRxiv · Jan 11, 2023Biophysics