Author

M. Faronato

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. W. Tate· 2 shared R. Solari· 2 shared A. Chronopoulos· 1 shared A. del Rio Hernandez· 1 shared A. Farrugia· 1 shared A. Gorelik· 1 shared A. Goya Grocin· 1 shared A. Lim· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

E. W. Tate

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry

L. Priyamvada, W. W. Kallemeijn, M. Faronato, K. Wilkins, C. S. Goldsmith, C. A. Cotter, S. Ojeda, R. Solari, B. Moss, E. W. Tate, P. S. Satheshkumar

This study shows that IMP-1088 inhibits vaccinia virus infection by blocking N-myristoylation of viral protein L1, leading to non-infectious virions.

bioRxiv · Jun 13, 2022Microbiology

N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers

G. A. Lueg, M. Faronato, A. Gorelik, A. Goya Grocin, E. Caamano-Gutierrez, F. Falciani, R. Solari, R. Carr, A. S. Bell, E. Bartlett, J. A. Hutton, M. Llorian-Sopena, P. Chakravarty, B. Brzezicha, M. Janz, , E. W. Tate

N-myristoyltransferase inhibition causes mitochondrial dysfunction and cell death in MYC-deregulated cancers through post-transcriptional failure in complex I synthesis.

bioRxiv · Mar 20, 2021 · PreprintCancer Biology

SREBP1 drives KRT80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer

L. Magnani, Y. Perone, A. Farrugia, A. Meira, B. Gyorffy, C. Ion, A. Uggetti, D. Patten, A. Chronopoulos, M. Faronato, S. Shousha, J. Steel, C. Davies, N. Patel, A. del Rio Hernandez, , F. Calvo

This study identifies SREBP1-driven KRT80 upregulation as a mechanism promoting invasion in endocrine-resistant ERα breast cancer through cytoskeletal changes and increased tumor stiffness.

bioRxiv · Jul 30, 2018Cancer Biology