Evolution of cullin E3 ubiquitin ligases and function in trypanosomes
R. C. del Pino, M. Zoltner, K. Yamada, E. R. Butterfield, M. Field
The paper reconstructs the evolution of cullin-RING E3 ubiquitin ligases across eukaryotes and experimentally characterizes two cullin complexes in trypanosomatids, revealing lineage-specific diversity and novel substrate specificity.
bioRxiv · Jul 24, 2023 · PreprintCell Biology