IL-10 inhibits STAT1-dependent macrophage accumulation during microbiota-induced colitis
I. Patik, N. S. Redhu, A. Eran, B. Bao, A. Nandy, Y. Tang, S. El Sayed, Z. Shen, J. Glickman, J. G. Fox, S. Snapper, B. H. Horwitz
The paper shows IL-10R inhibits STAT1-dependent macrophage accumulation in colitis by preventing a cell-extrinsic signal, not directly affecting STAT1 function.
Mucosal Immunology · Jun 1, 2023Peer-reviewedImmunology