Author

M. Filius

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 3 Approach:deep learning· 2 Assay:fluorescence / live-cell microscopy· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

C. Joo· 6 shared D. de Ridder· 3 shared S. H. Kim· 3 shared C. de Lannoy· 2 shared R. van Wee· 2 shared A. Ananth· 1 shared A. S. Meyer· 1 shared C. de Agrela Pinto· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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6 shared papersBiophysics

C. Joo

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Author profile →

6 papers

Recent·Most cited

Full-Length Single-Molecule Protein Fingerprinting

M. Filius, R. van Wee, C. de Lannoy, I. Westerlaken, Z. Li, S. H. Kim, C. de Agrela Pinto, Y. Wu, G.-J. Boons, M. Pabst, D. de Ridder, C. Joo

This paper introduces a method to map amino acid positions and post-translational modifications in single protein molecules with sub-nanometer resolution using FRET-based single-molecule protein fingerprinting.

bioRxiv · Sep 26, 2023Biophysics

Evaluation of FRET X for Single-Molecule Protein Fingerprinting

C. de Lannoy, M. Filius, R. van Wee, C. Joo, D. de Ridder

The paper evaluates FRET X fingerprinting for single-molecule protein identification through simulations and experiments, achieving 95% accuracy in identifying proteins from a complex mixture.

bioRxiv · Jun 30, 2021Biophysics

High-Resolution Single-Molecule FRET via DNA eXchange (FRET X)

M. Filius, S. H. Kim, I. Severins, C. Joo

This paper introduces FRET X, a method to measure multiple FRET pairs in single molecules with sub-nanometer resolution by using DNA strand exchange.

bioRxiv · Oct 15, 2020Biophysics

FRETboard: semi-supervised classification of FRET traces

C. V. de Lannoy, M. Filius, S. H. Kim, C. Joo, D. de Ridder

FRETboard is a semi-supervised tool for classifying FRET traces, improving efficiency and accuracy compared to manual methods and existing software.

bioRxiv · Aug 28, 2020Biophysics

High-Speed Super-Resolution Imaging Using Protein-Assisted DNA-PAINT

M. Filius, T. J. Cui, A. Ananth, M. Docter, J. Hegge, J. van der Oost, C. Joo

This paper introduces Ago-PAINT, a method that accelerates DNA-PAINT imaging by using Argonaute protein to enhance imager strand binding, achieving 10x faster acquisition without compromising resolution.

Nano Letters · Mar 13, 2020Peer-reviewedBiophysics

Single-Molecule Peptide Fingerprinting

J. van Ginkel, M. Filius, M. Szczepaniak, P. Tulinksi, A. S. Meyer, C. Joo

This paper introduces a single-molecule FRET-based technique for protein fingerprinting using ClpXP to sequence peptides with high processivity and low sample requirements.

bioRxiv · Nov 29, 2017Biophysics