ImmunologybioRxivPreprint
Divergent and dominant anti-inflammatory effects of patient-derived anti-citrullinated protein antibodies (ACPA) in arthritis development
B. Raposo, M. G. Afonso, L. Israelsson…·V. Malmström
This study shows that most patient-derived anti-citrullinated protein antibodies (ACPA) are anti-inflammatory, with some clones inhibiting arthritis while others promote disease, highlighting the complexity of ACPA's role in rheumatoid arthritis.
DOI 10.1101/2022.09.30.510377