Author

P. Luong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

B. A. Duerkop· 2 shared H. De Luca· 2 shared K. Hullahalli· 2 shared K. L. Palmer· 2 shared M. J. Grey· 2 shared M. S. Simpson· 2 shared W. I. Lencer· 2 shared A. Chatterjee· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

B. A. Duerkop

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Metabolic connections between folate and peptidoglycan pathways in Pseudomonas aeruginosa inform rational design of a dual-action inhibitor

L. N. Yaeger, D. Sycantha, P. Luong, S. Shekarriz, O. Goncalves, A. Dobrin, M. R. Ranieri, R. P. Lamers, H. Harvey, G. C. diCenzo, M. G. Surette, J.-P. Cote, J. Magolan, L. L. Burrows

This study identifies metabolic links between folate and peptidoglycan pathways in Pseudomonas aeruginosa and uses these insights to design a dual-action inhibitor that overcomes antibiotic resistance.

bioRxiv · Nov 22, 2023 · PreprintMicrobiology

Structural basis for recognition of unfolded proteins by the ER stress sensor ERN1/IRE1α

M. S. Simpson, H. De Luca, S. Cauthorn, P. Luong, N. Udeshi, T. Svinkina, S. S. Schmeider, S. A. Carr, M. J. Grey, W. I. Lencer

This study identifies a 7-residue motif in unfolded proteins recognized by IRE1LD, revealing how IRE1 detects misfolded proteins to trigger the UPR.

bioRxiv · Jun 20, 2023 · PreprintCell Biology

Targeted IS-element sequencing uncovers transposition dynamics during selective pressure in enterococci

J. M. Kirsch, S. Ely, M. E. Stellfox, K. Hullahalli, P. Luong, K. L. Palmer, D. Van Tyne, B. A. Duerkop

This study uses IS-Seq to show that phage infection and antibiotic exposure drive IS256 diversification in enterococci, linking selective pressures to genome evolution.

bioRxiv · Aug 24, 2022Microbiology

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress

M. J. Grey, E. Cloots, M. S. Simpson, N. LeDuc, Y. Serebrenik, H. De Luca, D. De Sutter, P. Luong, J. R. Thiagarajah, A. W. Paton, J. C. Paton, M. Seeliger, S. Eyckerman, S. Janssens, W. I. Lencer

This study shows IRE1β suppresses IRE1α signaling during ER stress by blocking its activation and disrupting a feedback loop that regulates IRE1 expression.

bioRxiv · Mar 23, 2019Cell Biology

Bacteriophage resistance alters antibiotic mediated intestinal expansion of enterococci

A. Chatterjee, C. N. Johnson, P. Luong, K. Hullahalli, S. W. McBride, A. M. Schubert, K. L. Palmer, P. E. Carlson, B. A. Duerkop

This study shows that phage resistance in enterococci reduces their intestinal colonization ability and antibiotic sensitivity, suggesting phage therapy could complement antibiotics in treating dysbiotic microbiota.

bioRxiv · Jan 26, 2019Microbiology