Author

M. Ganguly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:cryo-EM· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein structure prediction· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. K. Shukla· 3 shared J. Maharana· 3 shared P. Sarma· 3 shared R. Banerjee· 3 shared S. Saha· 3 shared V. Singh· 3 shared C. Soni· 2 shared M. Chami· 2 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

A. K. Shukla

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Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 3, 2023

Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution

M. Yadav, P. Sarma, M. Ganguly…·A. K. Shukla

This study presents cryo-EM structures of GPR109A-G-protein complexes with agonists and uses them to engineer biased agonists with reduced flushing effects.

DOI 10.1101/2023.07.03.547505

humancryo-EM

𝕏 PostBluesky

BiochemistrybioRxivPreprintFeb 9, 2023

Structural insights into agonist-binding and activation of the human complement C3a receptor

M. K. Yadav, R. Yadav, P. Sarma…·C. Gati

This study presents structural insights into C3a-C3aR interactions and identifies a G-protein-biased agonist for the receptor.

DOI 10.1101/2023.02.09.527835

humanprotein structure

𝕏 PostBluesky

BiophysicsbioRxivPreprintJan 14, 2023

Structural insights into ligand-recognition, activation, and signaling-bias at the complement C5a receptor, C5aR1

A. K. Shukla, S. Saha, J. Maharana…·R. Banerjee

This study presents cryo-EM structures of C5aR1 bound to C5a and a synthetic peptide, revealing conformational changes and G-protein coupling mechanisms.

DOI 10.1101/2023.01.14.524051

humancryo-EM

𝕏 PostBluesky