Cancer BiologybioRxiv
TGFβ receptor inhibition unleashes interferon-β production by tumor-associated macrophages and enhances radiotherapy efficacy
P. Hamon, M. Gerbe de Thore, M. Classe…·M. Mondini
This study shows that inhibiting TGFβ receptors in tumor-associated macrophages boosts interferon-β production and enhances radiotherapy effectiveness in mouse cancer models.
DOI 10.1136/jitc-2021-003519