Author

P. Hamon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

J. Le Berichel· 3 shared L. Troncoso· 3 shared M. D. Park· 3 shared A. Magen· 2 shared B. Giotti· 2 shared D. D'souza· 2 shared F. Ginhoux· 2 shared M. Belabed· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

J. Le Berichel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors

S. Hegde, B. Giotti, B. Y. Soong, L. Halasz, J. Le Berichel, A. Magen, B. Kloeckner, R. Mattiuz, M. D. Park, A. Marks, M. Belabed, P. Hamon, T. Chin, L. Troncoso, J. J. Lee, , M. Merad

The paper identifies NRF2-driven myeloid progenitor dysregulation that sustains immunosuppressive macrophages in tumors, showing NRF2 inhibition reduces their survival and enhances antitumor immunity.

bioRxiv · Jun 24, 2024Immunology

Circulating senescent myeloid cells drive blood brain barrier breakdown and neurodegeneration

C. M. Wilk, F. Cathomas, O. Torok, J. Le Berichel, M. D. Park, G. R. Heaton, P. Hamon, L. Troncoso, B. P. Scull, D. Dangoor, A. Silvin, R. Fleischmann, M. Belabed, H. Lin, E. M. Taouli, , M. Merad

This study identifies circulating senescent myeloid cells as drivers of blood-brain barrier breakdown and neurodegeneration in LCH-ND.

bioRxiv · Oct 10, 2023Cell Biology

Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade

A. Magen, P. Hamon, N. Fiaschi, L. Troncoso, E. Humblin, D. D'souza, T. Dawson, M. D. Park, J. Kim, S. Hamel, M. Buckup, C. Chang, A. Tabachnikova, H. Schwartz, N. Malissen, , Merad

The paper identifies intratumoral niches involving mregDC and CXCL13+ Th cells that support CD8 T cell differentiation following PD-1 blockade in HCC patients.

bioRxiv · Jun 22, 2022 · PreprintImmunology

TGFβ receptor inhibition unleashes interferon-β production by tumor-associated macrophages and enhances radiotherapy efficacy

P. Hamon, M. Gerbe de Thore, M. Classe, N. Signolle, W. Liu, O. Bawa, L. Meziani, C. Clemenson, F. Milliat, E. Deutsch, M. Mondini

This study shows that inhibiting TGFβ receptors in tumor-associated macrophages boosts interferon-β production and enhances radiotherapy effectiveness in mouse cancer models.

bioRxiv · Jan 17, 2022Cancer Biology

The last battle of Anne of Brittany: solving mass grave through an interdisciplinary approach (paleopathology, anthropobiology, history, multiple isotopes and radiocarbon dating)

R. Colleter, C. Bataille, S. Milano, H. Dabernat, M. Trost, M. Marchal, C. Guilbeau-Frugier, D. Pichot, P. Hamon, F. Labaune-Jean, S. Jean, G. Le Cloirec, S. Steinbrenner, S. Duchesne, N. Telmon, , K. Jaouen

This study identifies individuals in two Breton mass graves using interdisciplinary methods, revealing they were soldiers from opposing armies during the 1491 siege of Rennes.

bioRxiv · Feb 22, 2021Ecology