Cell BiologybioRxiv
Astroglia proliferate upon biogenesis of tunneling nanotubes and clearance of α-synuclein toxicities
A. Raghavan, R. Kashyap, S. P…·S. Nath
This study shows that α-synuclein protofibrils induce tunneling nanotube biogenesis in astrocytes, which facilitates clearance of toxic aggregates and reversal of cellular senescence, leading to enhanced proliferation.
DOI 10.1016/j.isci.2024.110565