Comprehensive chromatome profiling identifies metabolic enzymes on chromatin in healthy and cancer cells
S. Kourtis, M. Guirola, N. Pardo-Lorente, R. Ghose, M. Garcia-Cao, A. Ganez-Zapater, S. Haynes, F. Fontaine, A. Muller, S. Sdelci
The paper identifies widespread metabolic enzyme localization on chromatin in healthy and cancer cells, showing tissue-specific abundance and non-canonical roles in DNA damage and repair.
bioRxiv · Dec 6, 2023 · PreprintCancer Biology