BioengineeringbioRxiv
Towards Modular Engineering of Cell Signalling: Topographically-Textured Microparticles Induce Osteogenesis via Activation of Canonical Hedgehog Signalling
F. I. Ghuloum, L. A. Stevens, C. A. Johnson…·M. H. Amer
This study shows that topographically-textured microparticles activate Hedgehog signaling and induce osteogenesis in mesenchymal stem cells without exogenous factors.
DOI 10.1016/j.bioadv.2023.213652