D. Needham

GBP2 aggregates LPS and activates the caspase-4 inflammasome independent of the bacterial encapsulation factor GBP1

This paper shows GBP2 can trigger pyroptosis by aggregating free LPS and activating caspase-4, independent of GBP1's bacterial binding function.

Investigation of the futalosine pathway for menaquinone biosynthesis as a novel target in the inhibition of Chlamydia trachomatis infection

This study identifies the futalosine pathway as a target for inhibiting Chlamydia trachomatis infection using docosahexaenoic acid and shows that menaquinone-7 is essential for its survival.

The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology Motivates Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Contagious Variants, and Other Respiratory Viral Infections

This paper investigates how pH affects niclosamide solubility and dissolution, suggesting optimal formulations for mucin-penetrating nasal and throat sprays against respiratory viruses.

Designing Topographically Textured Microparticles For Induction and Modulation of Osteogenesis in Mesenchymal Stem Cell Engineering

This study shows that topographically textured microparticles can enhance osteogenic markers in mesenchymal stem cells without exogenous factors.

Taxon disappearance from microbiome analysis indicates need for mock communities as a standard in every sequencing run

The paper demonstrates that routine use of mock communities in microbiome sequencing detects hidden biases and aberrations that could otherwise go undetected, highlighting their necessity as a standard in every sequencing run.