MicrobiologybioRxiv
Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -{lambda}
M. Hayn, M. Hirschenberger, L. Koepke…·K. M. J. Sparrer
This study identifies SARS-CoV-2's vulnerability to IFN-γ and -λ due to its inefficient antagonism of type I and II IFN responses, suggesting potential therapeutic strategies.
DOI 10.1016/j.celrep.2021.109126