M. Harms

InCellCryst - A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins

InCellCryst produces homogeneous protein microcrystals within living insect cells, enabling X-ray diffraction data collection without protein purification.

Targeting of the human nasal microbiota by secretory IgA antibodies

This study identifies bacterial genera and species targeted by sIgA in the nasal microbiome using IgA-seq and sIgA deposition experiments, showing individual variation and epitope-independent interactions with S. aureus.

Acute myeloid leukemia cells are targeted by the naturally occurring CXCR4 antagonist EPI-X4

The paper was withdrawn due to unresolved data contribution and authorship issues, and the authors request it not be cited as a reference.

Natural Cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling

The paper identifies a Cystatin C fragment that inhibits GPR15-mediated HIV and SIV infection without affecting GPR15L signaling.

CXCR4 signaling is counteracted by the naturally occurring CXCR4 antagonist EPI-X 4 in Waldenstrom Macroglobulinemia

This study shows that the natural CXCR4 antagonist EPI-X4 inhibits Waldenstrom Macroglobulinemia cell growth and migration, with optimized derivatives showing enhanced efficacy.

Microtiter plate-based antibody-competition assay to determine binding affinities and plasma/blood stability of CXCR4 ligands

pytc: a python package for analysis of Isothermal Titration Calorimetry experiments

pytc is a Python package for analyzing Isothermal Titration Calorimetry data using global fits of thermodynamic models.