Author

M. Heim

Primary ORCID profile (0000-0002-7858-4822 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

M. HeimiD1 paper · Centre National de la Recherche Scientifique

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Geng· 1 shared B. Ludewig· 1 shared C. Bernsmeier· 1 shared C. J. Weston· 1 shared D. Semela· 1 shared E. E. Flint· 1 shared E. Yildiz· 1 shared G. Sorrentino· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Geng

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Distinct circulating monocytes up-regulate CD52 and sustain innate immune function in patients with cirrhosis unless acute decompensation emerges

A. Geng, R. G. Brenig, J. Roux, M. Luetge, H.-W. Cheng, E. E. Flint, M.-A. Meier, O. T. Pop, P. Kuenzler-Heule, M. McPhail, S. Soysal, D. Semela, M. Heim, C. J. Weston, B. Ludewig, C. Bernsmeier

The paper identifies CD52-expressing monocytes in cirrhosis that enhance innate immunity, but their loss during acute decompensation correlates with infection and poor outcomes.

bioRxiv · Apr 3, 2024 · PreprintImmunology

Mechano-modulatory synthetic niches for liver organoid derivation

G. Sorrentino, S. Rezakhani, E. Yildiz, S. Nuciforo, M. Heim, M. Lutolf, K. Schoonjans

This study develops chemically defined hydrogels to derive mouse and human liver organoids, showing stiffness sensitivity and YAP/SFK dependence, and establishes biopsy-derived human liver organoids without animal components.

bioRxiv · Oct 18, 2019Bioengineering