Author

A. Geng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

C. Bernsmeier· 2 shared D. Semela· 2 shared E. E. Flint· 2 shared J. Roux· 2 shared O. T. Pop· 2 shared R. G. Brenig· 2 shared A. Manghrani· 1 shared A. Singanayagam· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

C. Bernsmeier

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Distinct circulating monocytes up-regulate CD52 and sustain innate immune function in patients with cirrhosis unless acute decompensation emerges

A. Geng, R. G. Brenig, J. Roux, M. Luetge, H.-W. Cheng, E. E. Flint, M.-A. Meier, O. T. Pop, P. Kuenzler-Heule, M. McPhail, S. Soysal, D. Semela, M. Heim, C. J. Weston, B. Ludewig, C. Bernsmeier

The paper identifies CD52-expressing monocytes in cirrhosis that enhance innate immunity, but their loss during acute decompensation correlates with infection and poor outcomes.

bioRxiv · Apr 3, 2024 · PreprintImmunology

Targeting the expansion of myeloid-derived suppressor cells in liver cirrhosis

E. E. Flint, C. Ercan, E. Mitchell, O. T. Pop, A. Geng, P. Jorzik, L. A. Possamai, R. G. Brenig, S. Morel, P. Sieber, A. Singanayagam, M. S. Matter, D. Semela, M. H. E. Heim, P. Demougin, , C. Bernsmeier

This study investigates MDSC expansion in cirrhosis patients and murine models, showing poly(I:C) reduces MDSC and fibrosis in infected fibrotic mice.

bioRxiv · Mar 29, 2024 · PreprintImmunology

RNA conformational propensities determine cellular activity

M. L. Kelly, R. Roy, A. Geng, L. R. Ganser, A. Manghrani, B. R. Cullen, U. Schulze-Gahmen, D. Herschlag, H. M. Al-Hashimi

The paper alters and measures conformational propensities of HIV-1 TAR RNA to predict binding affinities and cellular activity.

bioRxiv · Dec 5, 2022 · PreprintBiophysics