ImmunologybioRxivPreprint
Extracellular vesicles carrying HIV-1 Nef induce trained immunity in myeloid cells
L. Dubrovsky, B. Brichacek, N. M. Prashant…·M. I. Bukrinsky
The paper shows that HIV-1 Nef-containing extracellular vesicles induce trained immunity in myeloid cells through epigenetic changes and lipid raft upregulation, leading to persistent inflammation.
DOI 10.1101/2022.06.24.497538