M. Igarashi

Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway

This study shows nicotine increases intestinal stem cell stemness and tumorigenicity through Hippo-YAP/TAZ and Notch pathways, and suggests DBZ as a potential therapeutic.

Evasion of APOBEC1-mediated Intrinsic Immunity by a Herpesvirus Uracil DNA Glycosylase Is a Determinant of Viral Encephalitis

This study shows that HSV-1's vUNG enzyme evades APOBEC1 immunity by preventing DNA editing, leading to more severe encephalitis in mice.

A land plant specific VPS13 mediates polarized vesicle trafficking in germinating pollen

This study identifies AtVPS13a as a plant-specific protein required for directional vesicle trafficking during Arabidopsis pollen germination, linking it to pollen tube growth and cell wall deposition.

Collection of 2429 constrained headshots of 277 volunteers for deep learning

The paper collects 2429 constrained headshots of 277 volunteers for deep learning, demonstrating its utility for gender recognition with convolutional neural networks.

Influenza A virus agnostic receptor tropism revealed using a novel biological system with terminal sialic acid-knockout cells

This paper introduces a novel system using sialic acid receptor-knockout cells to study influenza A virus receptor tropism, revealing unique biological tropism undetectable by conventional assays.

Structural insight into Marburg virus nucleoprotein-RNA complex formation

This study determines the structure of the Marburg virus NP-RNA complex using cryo-EM, revealing conserved residues critical for nucleocapsid formation and RNA synthesis between MARV and EBOV.