SARS-CoV-2-neutralizing humoral IgA response occurs earlier but modest and diminishes faster compared to IgG response.
Y. Takamatsu, K. Omata, Y. Shimizu…·H. Mitsuya
This study compares the neutralizing activity of IgA and IgG antibodies against SARS-CoV-2 in COVID-19 patients and vaccine recipients, finding that IgA response is modest, peaks earlier, and declines faster than IgG.