Author

A. Robert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Ecology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

C. Vandier· 3 shared D. Crottes· 3 shared M. Gueguinou· 3 shared A. Charmantier· 2 shared G. Fromont-Hankard· 2 shared I. E. Elkholi· 2 shared J. Bourgeais· 2 shared J.-F. Cote· 2 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

C. Vandier

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Investigation of the heterogeneity of cancer cells using single cell calcium profiling.

A. Bura, C. Caussette, M. Gueguinou, D. Bellanger, A. Robert, M. Cancel, M. Lacouette-Rata, G. Fromont-Hankard, C. Vandier, K. Maheo, T. Brouard, D. Crottes

This study uses single cell calcium profiling combined with machine learning to analyze Ca2+ signature heterogeneity in cancer cells and their remodeling during resistance and cell interactions.

bioRxiv · Jan 14, 2024Cancer Biology

Encoding of the colorectal cancer metabolic program through MICU2

A. Robert, D. Crottes, J. Bourgeais, N. Gueguen, A. Chevrollier, J.-F. Dumas, S. Servais, I. Domingo, S. Chadet, J. Sobilo, O. Herault, T. Lecomte, C. Vandier, W. Raoul, M. Gueguinou

This study investigates the role of MICU2 in colorectal cancer metabolism, showing its importance in mitochondrial function, metabolic flexibility, and tumor progression.

bioRxiv · Oct 31, 2023 · PreprintCancer Biology

Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation

I. E. Elkholi, A. Robert, C. Malouf, H. Kuasne, S. Drapela, G. Macleod, S. Hebert, A. Pacis, V. Calderon, C. L. Kleinman, A. P. Gomes, J. A. Aguirre-Ghiso, M. Park, S. Angers, J.-F. Cote

This study identifies Pik3c3 as a vulnerability in dormancy-prone breast cancer cells, showing its inhibition reduces metastasis in preclinical models.

bioRxiv · Aug 2, 2023Cancer Biology

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex

I. E. Elkholi, J. Boulais, M.-P. Thibault, H.-D. Phan, A. Robert, L. B. Lai, D. Faubert, M. J. Smith, V. Gopalan, J.-F. Cote

bioRxiv · May 11, 2023Biochemistry

Curcumin and NCLX Inhibitors Share Anti-Tumoral Mechanisms in Microsatellite-Instability-Driven Colorectal Cancer

M. Gueguinou, S. Ibrahim, J. Bourgeais, A. Robert, T. Pathak, X. Zhang, D. Crottes, J. Dupuy, D. Ternant, V. Monbet, R. Guibon, H. Flores-Romero, A. Lefevre, S. Lerondel, A. Le Pape, , T. Lecomte

This study identifies NCLX as a therapeutic target in MSI-driven CRC, showing that curcumin and NCLX inhibitors induce anti-tumoral effects through mitochondrial calcium overload and apoptosis.

bioRxiv · Jan 18, 2022Cancer Biology

Identifying drivers of spatio-temporal variation in survival in four blue tit populations

O. Bastianelli, A. Robert, C. Doutrelant, C. de Franceschi, P. Giovannini, A. Charmantier

This study examines survival variation in four blue tit populations, finding synchronous survival fluctuations but no climate correlation, and a decline in two populations.

bioRxiv · Jan 28, 2021Ecology

Is earlier reproduction associated with higher or lower survival? Antagonistic results between individual and population scales in the blue tit

O. Bastianelli, A. Charmantier, C. Biard, S. Bonamour, C. Teplitsky, A. Robert

This study examines the relationship between breeding phenology and adult survival in blue tits, finding conflicting effects at population and individual scales.

bioRxiv · Jan 11, 2021 · PreprintEcology