Cell BiologybioRxiv
N-WASP-dependent branched actin polymerization attenuates B-cell receptor signaling by increasing the molecular density of receptor clusters
A. Bhanja, M. K. Seeley-Fallen, M. Lazzaro…·W. Song
This study shows that N-WASP-dependent branched actin polymerization drives B-cell contraction, which reduces BCR signaling by increasing receptor cluster molecular density and displacing signaling molecules.
DOI 10.7554/elife.87833