BiophysicsPLOS Computational BiologyPeer-reviewed
Signaling through polymerization and degradation: Analysis and simulations of T cell activation mediated by Bcl10
L. Campanello, M. K. Traver, H. Shroff…·W. Losert
This paper quantifies Bcl10 filament dynamics in T cell activation using microscopy and simulations, showing degradation at filament ends controls response timing.