Author

M. Kovatcheva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. Serrano· 3 shared C. Stephan-Otto Attolini· 2 shared J. Capellades· 2 shared O. Yanes· 2 shared A. Balvay· 1 shared A. Caballe· 1 shared A. E. Lord· 1 shared A. Garcia-Garijo· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCancer Biology

M. Serrano

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Persister cancer cells are characterized by H4K20me3 heterochromatin that defines a low inflammatory profile

V. Ramponi, L. Richart, M. Kovatcheva, C. Stephan-Otto Attolini, J. Capellades, A. E. Lord, O. Yanes, G. Ficz, M. Serrano

This study identifies H4K20me3 heterochromatin in persister cancer cells, which reduces their inflammatory profile and reveals vulnerabilities in one-carbon metabolism.

bioRxiv · Jan 26, 2024 · PreprintCancer Biology

A targeted metabolomic method to detect epigenetically relevant metabolites

J. Miro-Blanch, A. Junza, J. Capellades, A. Balvay, C. Moudet, M. Kovatcheva, S. Raineri, S. Rabot, J. Mellor, M. Serrano, O. Yanes

The paper introduces a targeted metabolomic method to detect epigenetically relevant metabolites using biphasic extraction and stable isotope tracing.

bioRxiv · Nov 30, 2023Biochemistry

Induction of senescence renders cancer cells highly immunogenic

I. Marin, O. Boix, A. Garcia-Garijo, i. Sirois, A. Caballe, E. Zarzuela, I. Ruano, C. Stephan-Otto Attolini, N. Prats, J. A. Lopez-Dominguez, M. Kovatcheva, E. Garralda, J. Munoz, E. Caron, M. Abad, , M. Serrano

This study shows that inducing senescence in cancer cells enhances their immunogenicity, leading to stronger anti-tumor immune responses compared to immunogenic cell death.

bioRxiv · Jun 5, 2022 · PreprintCancer Biology