Fitness Factor Genes Conserved within the Multi-species Core Genome of Gram-negative Enterobacterales Species Contribute to Bacteremia Pathogenesis
H. L. T. Mobley, M. T. Anderson, B. L. Moricz, G. S. Severin, C. L. Holmes, E. N. Ottosen, T. Eichler, S. Gupta, S. Paudel, R. Sinha, S. Mason, S. D. Himpsl, A. N. Brown, M. L. Gaca, C. M. Kiser, , M. A. Bachman
The paper identifies 18 conserved fitness genes in Enterobacterales species that contribute to bacteremia pathogenesis by testing mutants in a mouse model and finding attenuation in multiple organs.
bioRxiv · Mar 18, 2024Microbiology