S. Paudel

Fitness Factor Genes Conserved within the Multi-species Core Genome of Gram-negative Enterobacterales Species Contribute to Bacteremia Pathogenesis

The paper identifies 18 conserved fitness genes in Enterobacterales species that contribute to bacteremia pathogenesis by testing mutants in a mouse model and finding attenuation in multiple organs.

Thiosulfinate tolerance gene clusters are common features of Burkholderia onion pathogens.

This study identifies thiosulfinate tolerance gene clusters in onion-associated Burkholderia species and shows their role in allicin tolerance and growth in onion extracts.

NLRP3 inflammasome is dispensable in methicillin resistant Staphylococcus aureus urinary tract infection

This study shows that NLRP3 inflammasome is not required for immune defenses against MRSA urinary tract infection in mice.

Defining the roles of pyruvate oxidation, TCA cycle, and mannitol metabolism in methicillin resistance Staphylococcus aureus urinary tract infection

This paper identifies metabolic pathways critical for MRSA survival in urinary tract infections and suggests potential therapeutic targets.

Uterine histotroph and conceptus development. III. Adrenomedullin stimulates proliferation, migration and adhesion of porcine trophectoderm cells via AKT-TSC2-MTOR cell signaling pathway.

Human urine alters methicillin-resistant Staphylococcus aureus virulence and transcriptome

This study shows human urine alters MRSA virulence and transcriptome, affecting metabolic pathways, adherence, and surface properties.

In-stream habitat availability for river dolphins in response to flow: use of ecological integrity to manage river flows

This study quantifies the relationship between river flow and usable habitat area for Ganges River dolphins during low water seasons, showing flow impacts on distribution and abundance.

Thyroid Hormones-Thyrotropin Interrelationships in Thyroid Dysfunction States

This study examines the correlations between FT3, FT4, and TSH in thyroid dysfunction states using statistical modeling and clinical data from 3425 patients.

The effects of e-cigarette vapor exposure on the transcriptome and virulence of Streptococcus pneumoniae

This study examines how e-cigarette vapor affects the transcriptome and virulence of Streptococcus pneumoniae, finding nicotine-dependent transcriptome changes without affecting virulence.

Folding latency of fluorescent proteins affects the mitochondrial localization of fusion protein

The paper shows that faster folding fluorescent proteins can mislocalize mitochondrial-targeted fusion proteins, and slowing their folding improves mitochondrial localization.