Author

E. Stephenson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 8 Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Assay:scRNA-seq· 6 Research Focus:differential expression· 5 Approach:statistical model· 4 Research Focus:cell-cell communication· 3 Research Focus:gene regulatory network inference· 3

Frequent Co-Authors

K. Polanski· 5 shared J. Engelbert· 4 shared M. Haniffa· 4 shared M. R. Clatworthy· 4 shared S. A. Teichmann· 4 shared C. Dominguez Conde· 3 shared E. Dann· 3 shared J.-E. Park· 3 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

K. Polanski

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

A spatial human thymus cell atlas mapped to a continuous tissue axis

N. Yayon, V. R. Kedlian, L. Boehme, C. Suo, B. Wachter, R. T. Beuschel, O. Amsalem, K. Polanski, S. Koplev, E. Tuck, E. Dann, J. Van Hulle, S. Perera, T. Putteman, A. V. Predeus, , Tag

The paper maps the spatial organization of the human thymus across developmental stages using a multimodal atlas and identifies key cellular and molecular features of T cell development.

bioRxiv · Oct 25, 2023Immunology

Experimental and mathematical models of intracellular calcium dynamics for evaluating combined anticancer effects of Afatinib and RP4010 in esophageal cancer

Y. Chang, M. T. Funk, S. Roy, E. Stephenson, S. Choi, H. Kojouharov, B. Chen, Z. PAN

International Journal of Molecular Sciences · Feb 3, 2022Peer-reviewedCancer Biology

Mapping the developing human immune system across organs

C. Suo, E. Dann, I. Goh, L. Jardine, V. Kleshchevnikov, J.-E. Park, R. A. Botting, E. Stephenson, J. Engelbert, Z. K. Tuong, K. Polanski, N. Yayon, C. Xu, O. Suchanek, R. Elmentaite, , S. A. Teichmann

This study maps the developing human immune system across organs using single-cell RNA sequencing, antigen-receptor sequencing, and spatial transcriptomics, revealing cross-gestation and cross-organ variability and identifying prenatal B1 cells and unconventional T cell origins.

bioRxiv · Jan 17, 2022Immunology

Obesity associated with attenuated tissue immune cell responses in COVID-19

S. A. Guo, G. S. Bowyer, J. R. Ferdinand, M. Maes, Z. K. Tuong, E. Gilman, M. Liao, R. G. H. Lindeboom, M. Yoshida, K. Worlock, H. Gopee, E. Stephenson, P. A. Lyons, K. G. C. Smith, M. Haniffa, , M. R. Clatworthy

The paper finds that obesity is associated with reduced immune and inflammatory responses in COVID-19 patients, including lower expression of IFN and IFNγ response genes in lung and blood cells.

bioRxiv · Jan 14, 2022 · PreprintImmunology

Conjunctival epithelial cells resist productive SARS-CoV-2 infection

M. Lako, R. M. Jackson, C. F. Hatton, J. S. Spegarova, M. Georgiou, J. Collin, E. Stephenson, B. Vernon, I. J. Haq, R. Hussain, J. M. Coxhead, H. S. Mudhar, B. Wagner, M. Hasoon, T. Davie, , C. J. Duncan

The paper investigates whether conjunctival epithelial cells can be infected by SARS-CoV-2 and finds that while genome expression occurs, productive infection does not.

bioRxiv · Dec 20, 2021Cell Biology

Cells of the human intestinal tract mapped across space and time

R. Elmentaite, N. Kumasaka, H. W. King, K. Roberts, M. Dabrowska, S. Pritchard, L. Bolt, S. F. Vieira, L. Mamanova, N. Huang, I. Goh Kai'En, E. Stephenson, J. Engelbert, R. A. Botting, A. Fleming, , S. A. Teichmann

The paper maps human intestinal cell lineages across development and disease, identifying new cell types and functions related to inflammation and immunity.

bioRxiv · Apr 7, 2021Cell Biology

Poised cell circuits in human skin are activated in disease

G. Reynolds, P. Vegh, J. Fletcher, E. Poyner, E. Stephenson, I. Goh, R. Botting, N. Huang, B. Olabi, A. Dubois, D. Dixon, K. Green, D. Maunder, J. Engelbert, M. Efremova, , F. Watt

The paper creates a single-cell atlas of human skin, showing how cell circuits change in inflammatory diseases like atopic dermatitis and psoriasis.

bioRxiv · Nov 5, 2020 · PreprintImmunology

A cell atlas of human thymic development defines T cell repertoire formation

J.-E. Park, R. A. Botting, C. Dominguez Conde, D.-M. Popescu, M. Lavaert, D. J. Kunz, E. Stephenson, R. Ragazzini, E. Tuck, A. L. Wilbrey-Clark, J. R. Ferdinand, S. Webb, D. Maunder, N. Vandamme, K. T. Mahbubani, , S. A. Teichmann

This study creates a cell atlas of the human thymus using scRNA-seq, revealing new cell populations and insights into T-cell development and TCR recombination.

bioRxiv · Jan 28, 2020Immunology