Author

L. Armstrong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. Collin· 2 shared M. Georgiou· 2 shared M. Lako· 2 shared A. Buskin· 1 shared A. Hope· 1 shared B. Vernon· 1 shared B. Wagner· 1 shared C. F. Hatton· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

J. Collin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Is it what's inside that matters? A conserved microbiome in woody tissues of Pinus radiata

K. Daley, Y. Eslami, L. Armstrong, K. Wigley, S. A. Wakelin

The paper examines the microbiome composition in different tissues of Pinus radiata trees, finding distinct microbial communities in various wood and bark tissues.

bioRxiv · Aug 10, 2023 · PreprintMicrobiology

Non-Canonical Functions of a Mutant TSC2 Protein in Mitotic Division

M.-B. L. Chalkley, R. B. Mersfelder, M. Sundberg, L. Armstrong, M. Sahin, R. A. Ihrie, K. Ess

This study identifies a novel mTORC1-independent multipolar mitotic division phenotype in TSC2 mutant iPSCs, suggesting non-canonical functions of mutant TSC2.

bioRxiv · Dec 7, 2022 · PreprintCell Biology

Conjunctival epithelial cells resist productive SARS-CoV-2 infection

M. Lako, R. M. Jackson, C. F. Hatton, J. S. Spegarova, M. Georgiou, J. Collin, E. Stephenson, B. Vernon, I. J. Haq, R. Hussain, J. M. Coxhead, H. S. Mudhar, B. Wagner, M. Hasoon, T. Davie, , C. J. Duncan

The paper investigates whether conjunctival epithelial cells can be infected by SARS-CoV-2 and finds that while genome expression occurs, productive infection does not.

bioRxiv · Dec 20, 2021Cell Biology

Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy

M. Georgiou, C. Yang, R. Atkinson, K.-T. Pan, A. Buskin, M. Moya Molina, J. Collin, J. Al-Aama, F. Goertler, S. E. J. Ludwig, T. Davey, R. Luhrmann, S. Nagaraja-Grellscheid, C. Johnson, R. Ali, , M. Lako

This study shows that PRPF31 mutations cause progressive protein aggregation in RPE cells, which can be reversed by autophagy activation.

bioRxiv · Oct 11, 2021 · PreprintCell Biology

Characterization of protease activity of Nsp3 from SARS-CoV-2 and its in vitro inhibition by nanobodies

L. Armstrong, S. M. Lange, V. de Cesare, S. P. Matthews, R. S. Nirujogi, I. Cole, A. Hope, F. Cunningham, R. Toth, R. Mukherjee, D. Bojkova, F. Gruber, D. Gray, P. G. Wyatt, J. Cinatl, , Y. Kulathu

This study characterizes Nsp3 protease activity from SARS-CoV-2 and identifies nanobodies that inhibit PLpro with nanomolar affinity.

bioRxiv · Dec 9, 2020Biochemistry