Author

M. Lor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Suhrbier· 2 shared D. J. Rawle· 2 shared T. Dumenil· 2 shared A. A. Khromykh· 1 shared A. Ullah· 1 shared B. F. Curren· 1 shared B. Griffen· 1 shared B. Tang· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Suhrbier

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dual therapy with corticosteroid ablates the beneficial effect of DP2 antagonism in chronic experimental asthma.

A. Ullah, S. Rittchen, J. Li, B. F. Curren, M. M. Rahman, M. A. A. Sikder, R. B. Rashid, N. Collinson, M. Lor, M. L. Smythe, S. Phipps

This study shows that combining DP2 antagonism with corticosteroids reduces the effectiveness of DP2 antagonism in treating chronic asthma by suppressing PGD2 and IFN-γ production.

bioRxiv · Nov 12, 2023Immunology

Increased neurovirulence of omicron BA.5 and XBB variants over BA.1 in K18-hACE2 mice and human brain organoids

R. Stewart, K. Yan, S. A. Ellis, C. R. Bishop, T. Dumenil, B. Tang, W. Nguyen, T. Larcher, R. Parry, J. D. J. Sng, A. A. Khromykh, R. K. P. Sullivan, M. Lor, F. A. Meunier, D. J. Rawle, A. Suhrbier

This study shows that omicron BA.5 and XBB variants are more neurovirulent than BA.1 in mice and human brain organoids, leading to increased brain infection and mortality.

bioRxiv · Dec 22, 2022 · PreprintMicrobiology

Bromodomain and Extraterminal Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection (Pre-Clinical)

R. J. Mills, S. J. Humphrey, P. R. Fortuna, M. Lor, S. R. Foster, G. A. Quaife-Ryan, R. L. Johnston, T. Dumenil, C. Bishop, R. Ruraraju, D. J. Rawle, T. Le, W. Zhao, L. Lee, C. Mackenzie-Kludas, , E

The paper identifies BET inhibitors as potential cardio-protective drugs that block inflammation-induced cardiac dysfunction and SARS-CoV-2 infection in pre-clinical models.

bioRxiv · Aug 23, 2020 · PreprintCell Biology